Related Experiment Video

Updated: Feb 16, 2026

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn
11:27

A Modified Sonographic Algorithm for Image Acquisition in Life-Threatening Emergencies in the Critically Ill Newborn

Published on: April 7, 2023

7.5K

WINROP algorithm for prediction of sight threatening retinopathy of prematurity: Initial experience in Indian preterm

Gaurav Sanghi1, Anil Narang2, Sunny Narula3

  • 1Department of Vitreo-Retina, Sangam Netralaya, Mohali, Punjab, India.

Indian Journal of Ophthalmology
|December 29, 2017
PubMed

Insights

The WINROP tool shows high sensitivity (90.32%) in detecting sight-threatening retinopathy of prematurity (ROP) in Indian preterm infants. Further algorithm refinement may enhance its clinical utility for ophthalmologists and neonatologists.

Area of Science:

  • Ophthalmology
  • Neonatology
  • Medical Technology

Background:

  • Retinopathy of prematurity (ROP) is a leading cause of blindness in preterm infants.
  • Early detection and treatment are crucial for preventing vision loss.
  • The WINROP tool utilizes weight gain patterns to predict ROP risk.

Purpose of the Study:

  • To evaluate the efficacy of the WINROP online monitoring tool.
  • To assess WINROP's ability to detect sight-threatening Type 1 ROP in Indian preterm infants.

Main Methods:

  • Seventy preterm infants (<32 weeks gestation) were enrolled.
  • Birth weight, gestational age, and weekly weight data were input into the WINROP algorithm.
  • Sensitivity, specificity, positive, and negative predictive values were calculated.

Main Results:

  • 31 (44.28%) infants developed Type 1 ROP.
  • WINROP signaled an alarm in 74.28% of all infants and 90.32% of those with Type 1 ROP.
  • The negative predictive value was 83.3%, while specificity was 38.46%.

Conclusions:

  • WINROP demonstrated high sensitivity in detecting Type 1 ROP in this Indian cohort.
  • The study is the first in India to use a weight gain-based algorithm for ROP prediction.
  • Population-specific algorithm adjustments could improve WINROP's clinical utility.
Abstract

More Related Videos

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting14:43

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting

Published on: January 12, 2018

13.6K
Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

673

Related Concept Videos

Sight Distance in a Vertical Curve01:29

Sight Distance in a Vertical Curve

Sight distance on vertical curves is critical in roadway design. It ensures drivers can see far enough ahead to identify and respond to hazards effectively. This directly impacts safety, driver comfort, and the overall efficiency of the transportation network.Vertical curves are classified into crest and sag curves based on their geometry. For crest curves, sight distance is determined by the line of sight between a driver's eye and a small object on the road's surface. Design parameters for...
404
Initiation of Translation02:33

Initiation of Translation

Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
First, the initiator tRNA must be selected from the pool of elongator tRNAs by eukaryotic initiation factor 2 (eIF2). The initiator tRNA (Met-tRNAi) has conserved sequence elements including modified bases at...
39.3K
Initiation of Translation02:33

Initiation of Translation

8.2K
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

VSEPR Theory for Determination of Electron Pair Geometries
46.2K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
435
Transcription Initiation01:47

Transcription Initiation

Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
The promoters and enhancers and their accessory proteins allow tight regulation of...
21.3K