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Updated: Feb 16, 2026

Membrane Remodeling of Giant Vesicles in Response to Localized Calcium Ion Gradients
Published on: July 16, 2018
Unusual intraconal localization of orbital giant cell angiofibroma
Meryem Altin Ekin1, Seyda Karadeniz Ugurlu1, Fulya Cakalagaoglu2
1Department of Ophthalmology, Izmir Katip Celebi University, Ataturk Training and Research Hospital, Izmir, Turkey.
Abstract:
Giant cell angiofibroma (GCA) is a recently reported rare soft-tissue tumor that can develop in various sites including orbit. Orbital GCAs were mainly located in the eyelid or extraconal regions such as lacrimal gland and conjunctiva. We report an atypical case of a GCA arising in the intraconal area of the orbit in a 65-year-old male patient. The tumor was excised in total by lateral orbitotomy. Histological and immunohistochemical features were consistent with the diagnosis of GCA. No recurrence was observed during the follow-up of over 2 years. GCA is a rare tumor that should be considered in the differential diagnosis of intraconal orbital tumors. Complete surgical removal is the current optimal treatment option.
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