Related Experiment Video

Updated: Feb 16, 2026

Author Spotlight: Advancing Understanding of Age-Related Lens Stiffness Changes
05:19

Author Spotlight: Advancing Understanding of Age-Related Lens Stiffness Changes

Published on: April 5, 2024

2.9K

DYNAMIC RETINA VESSEL COLOR CHANGE DURING OCULAR COMPRESSION IN SEVERE LIPEMIA RETINALIS

Maria Benson1, Robert W Wong1,2, Ryan C Young1,3

  • 1Austin Retina Associates, Austin, Texas.

Retinal Cases & Brief Reports
|December 29, 2017
PubMed

Insights

Dynamic color change in infant retinal vessels from white to coral pink was observed due to lipemia retinalis. This finding links disrupted laminar flow to altered blood appearance in familial hyperlipoproteinemia.

Area of Science:

  • Ophthalmology
  • Genetics
  • Pediatrics

Background:

  • Lipemia retinalis presents as milky-white retinal vessels.
  • Familial hyperlipoproteinemia can cause severe lipid abnormalities in infants.

Observation:

  • A 6-week-old infant with type 1b familial hyperlipoproteinemia exhibited lipemia retinalis.
  • Externally applied ocular pressure induced a dynamic color change in retinal arteries from white to coral pink.

Findings:

  • Genetic analysis identified a rare mutation in the APOC2 gene.
  • The observed color change is attributed to disrupted laminar flow and intermixing of erythrocytes and chylomicrons.

Implications:

  • This study is the first to describe this specific retinal vessel color change mechanism in lipemia retinalis.
  • Highlights a rare case of congenital hyperlipidemia in nonconsanguineous offspring.
Abstract

More Related Videos

Where You Cut Matters: A Dissection and Analysis Guide for the Spatial Orientation of the Mouse Retina from Ocular Landmarks08:42

Where You Cut Matters: A Dissection and Analysis Guide for the Spatial Orientation of the Mouse Retina from Ocular Landmarks

Published on: August 4, 2018

15.1K
An In Vivo Duo-color Method for Imaging Vascular Dynamics Following Contusive Spinal Cord Injury09:25

An In Vivo Duo-color Method for Imaging Vascular Dynamics Following Contusive Spinal Cord Injury

Published on: December 31, 2017

10.0K

Related Concept Videos

Global Climate Change01:50

Global Climate Change

Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
29.1K
Colors and Magnetism03:02

Colors and Magnetism

Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...
14.2K
Color Vision01:24

Color Vision

Color perception begins in the retina, the light-sensitive layer at the back of the eye. Two main theories explain how colors are seen: the trichromatic theory and the opponent-process theory. The trichromatic theory, proposed by Thomas Young in 1802 and extended by Hermann von Helmholtz in 1852, suggests that color vision is based on three types of cone receptors in the retina. These cones are sensitive to different but overlapping ranges of wavelengths corresponding to red, blue, and green.
1.6K
The Retina01:32

The Retina

The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
76.9K
Le Chatelier's Principle: Changing Concentration02:27

Le Chatelier's Principle: Changing Concentration

A system at equilibrium is in a state of dynamic balance, with forward and reverse reactions taking place at equal rates. If an equilibrium system is subjected to a change in conditions that affects these reaction rates differently (a stress), then the rates are no longer equal and the system is not at equilibrium. The system will subsequently experience a net reaction in the direction of a greater rate (a shift) that will re-establish the equilibrium. This phenomenon is summarized by Le...
66.2K
Rates of Change01:20

Rates of Change

The rate of change is a central concept in mathematics that quantifies how one variable varies in response to another. It serves as a foundational tool in modeling dynamic systems across disciplines such as physics, biology, economics, and engineering. Understanding both average and instantaneous rates of change enables the analysis of behavior in functions that describe real-world phenomena.Average Rate of ChangeFor a function f(x) defined over an interval [x1,x2], the average rate of change...
144