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Published on: August 21, 2021
Detection of hepatitis E virus genotypes 3 and 4 in pig farms in Korea
Yong-Hyun Kim1, Byung-Joo Park1, Hee-Seop Ahn1
1Department of Infectious Diseases, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea.
Abstract:
Zoonotic transmission of hepatitis E virus (HEV) is mostly mediated by HEV-3 and HEV-4 genotypes, and domestic pigs are an important reservoir of these genotypes. A survey of 14 pig farms in Korea revealed HEV RNA in 30 of 148 (20.3%) fecal samples. HEV-3a and HEV-4c subtypes were identified in five pig farms (35.7%) and two pig farms (14.3%), respectively. Phylogenetic analysis indicated that the isolated HEV strains were closely related to previously reported zoonotic strains in Korea. The results of the genetic analysis partially explain the possible source of the zoonotic transmission of HEV to humans in Korea.
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