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Published on: July 15, 2018
Diarylheptanoids from the fresh pericarps of Juglans sigillata
Jingjing Liang1, Xiaogang Peng1, Jia Zhou1
1a Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy , Tongji Medical College of Huazhong University of Science and Technology , Wuhan , People's Republic of China.
Abstract:
One new diarylheptanoid (3S)-3', 4″-epoxy-1-(4'-hydroxylphenyl)-7-(3″-hydroxylphenyl) heptane-3-hydroxy (1), together with eleven known ones (2-12), was isolated from the fresh pericarps of Juglans sigillata. Their structures were elucidated on the basis of extensive spectroscopic methods, including HR-ESI-MS, 1D and 2D-NMR. All isolates were evaluated for their cytotoxic activities in vitro against the growth of human cancer cells lines HT-29 and MCF-7 by MTT assay.
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