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Risperidone-induced Erythema Multiforme Minor.

Shreyas Shrikant Pendharkar1, Shilpa Avinash Telgote1, Amol Jadhav1

  • 1Department of Psychiatry, Government Medical College, Akola, Maharashtra, India.

Indian Journal of Psychological Medicine
|December 30, 2017
PubMed
Summary

Atypical antipsychotic agents rarely cause skin reactions. This case highlights a rare instance of risperidone-induced erythema multiforme minor, an adverse dermatologic reaction.

Keywords:
Dermatologic reactionserythema multiforme minorrisperidone

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Area of Science:

  • Dermatology
  • Psychiatry
  • Pharmacology

Background:

  • Antipsychotic medications are widely used for psychiatric disorders.
  • Adverse cutaneous reactions (ACRs) are known side effects of antipsychotics.
  • Atypical antipsychotics are generally associated with a lower incidence of ACRs compared to typical agents.

Observation:

  • A patient developed an erythematous, target-like rash.
  • The rash was diagnosed as erythema multiforme minor.
  • The patient was concurrently being treated with risperidone.

Findings:

  • The adverse dermatologic reaction was attributed to risperidone.
  • This represents a rare case of risperidone-induced erythema multiforme minor.
  • The reaction pattern suggests a hypersensitivity response to the medication.

Implications:

  • Clinicians should be aware of the potential for rare dermatologic reactions with atypical antipsychotics like risperidone.
  • Early recognition and management of drug-induced skin reactions are crucial.
  • Further pharmacovigilance may be needed to fully characterize the dermatologic safety profile of risperidone.