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Related Concept Videos

Physical Methods for Controlling Microbial Growth: Temperature01:23

Physical Methods for Controlling Microbial Growth: Temperature

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Heat is a widely used method to control microbial growth by targeting and denaturing cellular proteins, thereby killing or inactivating microbes. This method's effectiveness is quantified using parameters such as the thermal death point (TDP), thermal death time (TDT), and decimal reduction time (D value). TDP represents the lowest temperature at which all microorganisms in a liquid suspension are eliminated within 10 minutes, whereas TDT is the time necessary to achieve sterilization at a...
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The spontaneity of a process depends upon the temperature of the system. Phase transitions, for example, will proceed spontaneously in one direction or the other depending upon the temperature of the substance in question. Likewise, some chemical reactions can also exhibit temperature-dependent spontaneities. To illustrate this concept, the equation relating free energy change to the enthalpy and entropy changes for the process is considered:
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The body's temperature, measured in degrees, is determined by the balance between heat production and dissipation to the surrounding environment. For instance, if exercising vigorously, the body will produce more heat, causing sweat and dissipating that heat. Despite extreme environmental conditions and physical exertion, the human temperature-control system maintains a constant core body temperature (the temperature of deep tissues, which are the tissues located beneath the skin and other...
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Consistent with the law of mass action, an equilibrium stressed by a change in concentration will shift to re-establish equilibrium without any change in the value of the equilibrium constant, K. When an equilibrium shifts in response to a temperature change, however, it is re-established with a different relative composition that exhibits a different value for the equilibrium constant.
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Understanding heat transfer mechanisms is essential for understanding how our bodies maintain balance in different environmental conditions. When the environment is thermoneutral, the body is in a state of balance, neither using nor releasing energy to maintain its core temperature. However, when the environment is not thermoneutral, the body employs four heat transfer mechanisms to maintain homeostasis: conduction, convection, evaporation, and radiation. These mechanisms facilitate heat...
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Related Experiment Video

Updated: Feb 16, 2026

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
06:43

Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

Published on: November 21, 2017

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Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management.

Melissa I Naiman1, Maria Gray2, Joseph Haymore3

  • 1Center for Advanced Design, Research, and Exploration, University of Illinois at Chicago; Attune Medical.

Journal of Visualized Experiments : Jove
|December 30, 2017
PubMed
Summary
This summary is machine-generated.

A novel esophageal device offers a safe and effective method for patient temperature management. This approach provides accurate core temperature control, reducing risks associated with traditional surface or intravascular methods in critical care settings.

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Area of Science:

  • Critical care medicine
  • Thermoregulation
  • Biomedical engineering

Background:

  • Patient temperature control is crucial for various clinical conditions, including neuroprotection after ischemic events and managing fever.
  • Perioperative hypothermia can lead to adverse outcomes like increased blood loss and infections, necessitating effective warming strategies.
  • Existing temperature management technologies include surface devices and intravascular catheters, each with limitations.

Observation:

  • A new esophageal device, similar to an orogastric tube, facilitates efficient core heat transfer.
  • This device integrates with existing heat exchange units for automated temperature management using core temperature sensors.
  • Compared to surface methods, the esophageal approach minimizes shivering and avoids vascular access complications.

Findings:

  • The esophageal device demonstrates accurate maintenance of target patient temperatures.
  • It offers a low-risk alternative for temperature management in critical care.
  • Published data support the efficacy and safety of this esophageal approach.

Implications:

  • This technology presents a significant advancement in patient safety and care protocols.
  • It provides a less invasive and potentially more effective method for therapeutic hypothermia and fever management.
  • Wider adoption could reduce complications and improve patient outcomes in critical care settings.