Related Experiment Video
Updated: Feb 16, 2026
12:18
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
23.7K
Neonatal methicillin-resistant Staphylococcus aureus colonization and infection.
Yoko Shirai1,2, Hiroko Arai1, Kazutomo Tamaki1
1Department of Neonatology, Toho University Omori Hospital, Ota-ku, Tokyo, Japan.
Journal of Neonatal-Perinatal Medicine
|December 30, 2017
Summary
Methicillin-resistant Staphylococcus aureus (MRSA) is a threat in NICUs. Neonates with longer stays, lower birth weights, central lines, or digestive issues face higher MRSA infection risks.
Area of Science:
- Neonatal Intensive Care Unit (NICU) Infections
- Infectious Disease Epidemiology
- Bacterial Pathogenesis
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat in Neonatal Intensive Care Units (NICUs), causing life-threatening infections.
- Neonates, particularly those with very low birth weight or serious illnesses, are at high risk for MRSA colonization and infection due to invasive procedures.
- Preventing MRSA transmission is crucial in NICUs, where standard contact precautions and active surveillance cultures (ASC) are employed.
Purpose of the Study:
- To analyze the clinical characteristics of MRSA colonization and infection in neonates.
- To identify risk factors associated with MRSA colonization and infection in a Japanese perinatal care center.
Main Methods:
- Retrospective analysis of 1716 neonates hospitalized between January 2010 and December 2015.
- Comparison of clinical characteristics between MRSA-colonized and non-colonized neonates.
- Analysis of factors differentiating MRSA-colonized non-infected from MRSA-infected neonates.
Main Results:
- MRSA colonization was observed in 6.99% (120/1716) of neonates, with 33 developing MRSA infection.
- Statistically significant differences were found in duration of stay and birth weight between colonized and non-colonized neonates.
- Central venous catheterization and digestive system diseases were significantly associated with MRSA infection in colonized neonates.
Conclusions:
- Neonates undergoing central venous catheterization are at increased risk of MRSA infection, consistent with previous findings.
- Digestive system diseases in neonates warrant close attention due to a potential association with MRSA infection.
- Targeted surveillance and preventive strategies are essential for high-risk neonates in the NICU setting.
Related Concept Videos
02:22The Colonization of Land
37.9K
Changes in the environment of the early Earth drove the evolution of organisms. As prokaryotic organisms in the oceans began to photosynthesize, they produced oxygen. Eventually, oxygen saturated the oceans and entered the air, resulting in an increase in atmospheric oxygen concentration, known as the oxygen revolution approximately 2.3 billion years ago. Therefore, organisms that could use oxygen for cellular respiration had an advantage. More than 1.5 years ago, eukaryotic cells and...
37.9K
01:22Resistivity
4.6K
When a voltage is applied to a conductor, an electrical field is generated, and charges in the conductor feel the force due to the electrical field. The current density that results depends on the electrical field and the properties of the material. In some materials, including metals at a given temperature, the current density is approximately proportional to the electrical field. In these cases, the current density can be modeled as:
4.6K
01:19Resistance
6.1K
When a current moves through any conductor, the conductor causes some level of difficulty for the current to flow. The measure of that difficulty is known as the resistance of the material and is represented by R. Every material has its own resistance. In the case of conductors, heat is emitted whenever a current passes through them. Resistance depends on the resistivity of the material. Resistivity is a characteristic of the material used to fabricate electrical components, whereas the...
6.1K
01:16Equivalent Resistance
1.0K
In circuit analysis, situations often arise where resistors are neither in series nor parallel configurations. To tackle such scenarios, three-terminal equivalent networks like the wye (Y) (Figure 1 (a)) or tee (T) and delta (Δ) (Figure 1 (b)) or pi (π) networks come into play. These networks offer versatile solutions and are frequently encountered in various applications, including three-phase electrical systems, electrical filters, and matching networks.
1.0K
01:25Resistance and Conductance
534
A conductor's DC resistance at a given temperature is influenced by its resistivity, length, and cross-sectional area. Resistivity is an inherent property of the conductor material, with annealed copper serving as the international standard for measurement. For instance, the resistivity of hard-drawn aluminum at 20 degrees Celsius is 61% of the standard conductivity of annealed copper.
Various factors impact the resistance of a conductor. Spiraling in stranded conductors increases their...
Various factors impact the resistance of a conductor. Spiraling in stranded conductors increases their...
534
01:21Rolling Resistance
683
When a solid cylinder rolls steadily on a rigid surface, the normal force applied by the surface on the cylinder is perpendicular to the tangent at the contact point. However, since no materials are entirely rigid, the surface's reaction to the cylinder involves a range of normal pressures.
For instance, imagine a hard cylinder rolling on a comparatively soft surface. The cylinder's weight compresses the surface beneath it. As the cylinder moves, the material in front of it slows down due to...
For instance, imagine a hard cylinder rolling on a comparatively soft surface. The cylinder's weight compresses the surface beneath it. As the cylinder moves, the material in front of it slows down due to...
683