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Chronic Nocardia cyriacigeorgica Periprosthetic Knee Infection Successfully Treated with a Two-Stage Revision: A Case

Michael M Hadeed1, J Ryan MacDonell, Ian J Dempsey

  • 1Department of Orthopaedic Surgery (M.M.H., J.R.M., I.J.D., and J.A.B.) and Division of Infectious Disease and International Health, Department of Medicine (C.C.M.), University of Virginia, Charlottesville, Virginia.

JBJS Case Connector
|December 30, 2017
PubMed
Abstract

Insights

This case study details the successful treatment of a rare Nocardia cyriacigeorgica periprosthetic joint infection (PJI) following knee replacement. A modified, prolonged antibiotic regimen was key to managing this challenging bacterial infection.

Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Microbiology

Background:

  • Periprosthetic joint infection (PJI) is a severe complication of joint replacement surgery.
  • Rising incidence of PJI presents challenges with novel and difficult-to-treat infections.
  • Nocardia cyriacigeorgica is identified as a causative agent in a total knee arthroplasty PJI.

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