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Low-set ears and associated anomalies in human foetuses
Alfredo Nuñez-Castruita1, Norberto López-Serna1
1Department of Embryology, Faculty of Medicine of the Universidad Autónoma de Nuevo León, Monterrey, México, Av. Francisco I. Madero y Dr. Eduardo Aguirre Pequeño S/N, Col. Mitras Centro, Monterrey, N.L, C.P. 64460, México.
International Journal of Pediatric Otorhinolaryngology
|December 31, 2017
Summary
Low-set ears (LSE) were found in 1148 per 10,000 fetuses, with over 30% showing associated anomalies, particularly heart defects. This suggests LSE can be a key indicator of fetal abnormalities.
Area of Science:
- Embryology
- Developmental Biology
- Medical Genetics
Background:
- Low-set ears (LSE) are a potential physical marker in neonates.
- Understanding the prevalence and associated anomalies of LSE is crucial for early diagnosis.
Purpose of the Study:
- To determine the prevalence of low-set ears (LSE) in human fetuses.
- To analyze anomalies associated with LSE.
- To review potential developmental mechanisms involved in LSE.
Main Methods:
- Evaluation of 1759 human fetuses from spontaneous abortions.
- Determination of auricle position based on established morphological standards.
- Detailed external morphology examination and thoraco-abdominal microdissection.
Main Results:
- Prevalence of LSE was 1148 per 10,000 fetuses.
- 31.2% of fetuses with LSE had associated anomalies, significantly higher than the 7.4% in the normal ear group.
- Most frequent associated anomalies involved the heart (53.6%), digestive tract (23.9%), and urinary system (16.9%).
Conclusions:
- Low-set ears (LSE) serve as a sensitive indicator for major fetal anomalies.
- Systematic assessment of ear position in newborns is recommended for early detection.
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