Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Toxicity Testing in Animals01:23

Toxicity Testing in Animals

16
Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
16
Biological Effects of Radiation02:59

Biological Effects of Radiation

18.1K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
18.1K
Psychodynamic Perspectives on Personality01:27

Psychodynamic Perspectives on Personality

1.6K
The psychodynamic perspective in psychology asserts that most personality functions operate unconsciously, outside of awareness. This means that the motives and emotions driving behavior often remain hidden, automatically buried in the unconscious mind as a defense mechanism to shield us from psychological distress. According to this theory, the unconscious mind contains thoughts, memories, and emotions that are too disturbing to face directly.
Psychodynamic theorists argue that unconscious...
1.6K
Radiation: Applications01:17

Radiation: Applications

1.8K
The average temperature of Earth is the subject of much current discussion. Earth is in radiative contact with both the Sun and dark space; it receives almost all its energy from the radiation of the Sun and reflects some of it into outer space. Dark space is very cold, about 3 K, so Earth radiates energy into it. For instance, heat transfer occurs from soil and grasses, the rate of which can be so rapid that frost can occur on clear summer evenings, even in warm latitudes.
The average...
1.8K
Social Cognitive Perspective on Personality01:30

Social Cognitive Perspective on Personality

1.0K
Social cognitive perspectives on personality emphasize the importance of conscious awareness, beliefs, expectations, and goals in shaping behavior. These perspectives incorporate behaviorist principles, such as learning through reinforcement and conditioning, but extend beyond them by highlighting human reasoning and planning. Unlike traditional behaviorist views, social cognitive theory focuses on how individuals reflect on their past experiences and plan for future outcomes by considering...
1.0K
Absorption of Radiation01:05

Absorption of Radiation

1.3K
The rate of heat transfer by emitted radiation is described by the Stefan-Boltzmann law of radiation:
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction models of adverse outcomes following surgery and radiotherapy for breast cancer: a systematic review.

ESMO real world data and digital oncology·2026
Same author

Search for Subsolar-Mass Binaries in the First Half of Advanced LIGO's and Advanced Virgo's Third Observing Run.

Physical review letters·2022
Same author

Therapeutic mammaplasty is a safe and effective alternative to mastectomy with or without immediate breast reconstruction.

The British journal of surgery·2020
Same author

Personal View: Learning Healthcare System for Radiotherapy - Maximising the Opportunities and Minimising the Threats.

Clinical oncology (Royal College of Radiologists (Great Britain))·2020
Same author

Is it Time to Change Radiotherapy: The Dawning of Chronoradiotherapy?

Clinical oncology (Royal College of Radiologists (Great Britain))·2019
Same author

Genetic Variants Predict Optimal Timing of Radiotherapy to Reduce Side-effects in Breast Cancer Patients.

Clinical oncology (Royal College of Radiologists (Great Britain))·2018
Same journal

Concordance Between Planned and Delivered treatment for Head and Neck Cancer Patients Treated With Curative Intent: A Real-World Comparison of Under 70-year-olds With 70-year-olds and Over.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

A Novel Technique for Pain Management to Deliver a Course of Palliative Radiotherapy.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Broad-Spectrum Antibiotics are Associated with worse Survival After Radical Treatment for Glioblastoma Multiforme: A Multicentre Study.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Exploring the Need for Plan Adaptation in Robustly Optimised Head and Neck Intensity Modulated Proton Therapy: A Dosimetric Perspective From Initial Institutional Experience.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Lifting the Lid on Best Practice in a Case of Oligometastatic Breast Cancer.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
Same journal

Standardisation of Imaging Surveillance for Patients With Metastatic Melanoma Stopping Immune Checkpoint Inhibitors.

Clinical oncology (Royal College of Radiologists (Great Britain))·2026
See all related articles

Related Experiment Video

Updated: Feb 16, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

9.9K

The Patient Perspective on Radiogenomics Testing for Breast Radiation Toxicity.

T Rattay1, R P Symonds1, S Shokuhi2

  • 1Department of Cancer Studies, University of Leicester, Leicester, UK.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|December 31, 2017
PubMed
Summary
This summary is machine-generated.

Patients support radiogenomics testing for breast radiation toxicity but prefer results be given to healthcare professionals. Advance knowledge of radiation toxicity risk rarely influenced treatment decisions in this study.

Keywords:
breastpersonalised medicinequalitative researchradiogenomicsradiotherapytoxicity

More Related Videos

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
06:21

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Published on: May 27, 2016

8.6K
Establishment and Culture of Patient-Derived Breast Organoids
08:29

Establishment and Culture of Patient-Derived Breast Organoids

Published on: February 17, 2023

6.2K

Related Experiment Videos

Last Updated: Feb 16, 2026

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery
07:14

A Quantitative Sensory Testing Paradigm to Obtain Measures of Pain Processing in Patients Undergoing Breast Cancer Surgery

Published on: January 18, 2018

9.9K
Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model
06:21

Diffuse Optical Spectroscopy for the Quantitative Assessment of Acute Ionizing Radiation Induced Skin Toxicity Using a Mouse Model

Published on: May 27, 2016

8.6K
Establishment and Culture of Patient-Derived Breast Organoids
08:29

Establishment and Culture of Patient-Derived Breast Organoids

Published on: February 17, 2023

6.2K

Area of Science:

  • Oncology
  • Genetics
  • Radiotherapy

Background:

  • Radiogenomics offers potential genetic markers for predicting individual susceptibility to radiation toxicity.
  • Predictive models integrating radiogenomics are under development in the REQUITE trial.

Purpose of the Study:

  • To explore breast cancer patients' attitudes towards predictive radiogenomics testing for radiation toxicity.

Main Methods:

  • Semi-structured interviews were conducted with 21 breast cancer patients in the REQUITE study.
  • Inductive thematic analysis was used to identify common themes in patient attitudes.

Main Results:

  • Patients expressed willingness to undergo testing, emphasizing the need for information and trusted experts.
  • Key themes included implications of testing (preparation, anxiety) and its impact on treatment decisions (cancer cure, breast integrity, patient preferences).

Conclusions:

  • Patients generally support radiogenomics testing for breast radiation toxicity and trust its validity.
  • Results suggest a preference for results to be communicated via healthcare professionals.
  • Advance knowledge of toxicity risk had limited impact on treatment decisions, except in cases of severe symptoms or organ damage.