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Updated: Feb 16, 2026

A Murine Model of Subarachnoid Hemorrhage
Published on: November 21, 2013
Sexual Dysfunction After Good-Grade Aneurysmal Subarachnoid Hemorrhage.
Lorenz Epprecht1, Michael Messerli2, Robin Samuel3
1Department of Neurosurgery, Cantonal Hospital St. Gallen, St. Gallen, Switzerland; Department of Otorhinolaryngology Head and Heck Surgery, University Hospital Zurich, Zürich, Switzerland.
This study looked at how aneurysmal subarachnoid hemorrhage (aSAH) affects sexual function in patients with good neurological recovery. Researchers used standardized questionnaires to assess sexual function in 33 patients treated between 2005 and 2013. All patients had favorable outcomes on the Glasgow Outcome Scale. The findings showed that 31.3% of patients reported a decline in sexual pleasure after the hemorrhage. Among women, 47.4% met criteria for sexual dysfunction, with all 19 women experiencing hypoactive sexual desire disorder. Half of the male patients had erectile dysfunction. Patients with more severe aSAH (WFNS grade 2) were more likely to report sexual dysfunction than those with milder cases (WFNS grade 1). The study is the first to evaluate sexual health in this patient group and suggests that sexual dysfunction is common even when neurological outcomes are good. The authors recommend that sexual health be discussed during follow-up care for these patients.
Area of Science:
- Neurological outcomes research in clinical neurology
- Sexual health assessment in post-neurological injury
- Patient-reported outcomes in cerebrovascular disease
Background:
Prior research has shown that aneurysmal subarachnoid hemorrhage (aSAH) can lead to various neurological deficits. However, the impact on sexual function remains understudied. While some studies have explored physical recovery and cognitive outcomes, few have focused on sexual health in patients with favorable neurologic recovery. It was already known that aSAH can cause significant morbidity, but the specific effects on sexual pleasure were not well characterized. This gap motivated researchers to investigate whether sexual dysfunction persists even when neurological outcomes are favorable. No prior work had resolved the extent of sexual dysfunction in this patient group. The absence of data on subjective changes in sexual pleasure highlighted a need for further exploration. Understanding these effects could improve post-hospital care and patient quality of life. This study aimed to address these unanswered questions.
Purpose Of The Study:
The study aimed to evaluate the effects of aSAH on sexual function in patients with favorable neurologic outcomes. Researchers wanted to determine if sexual pleasure was affected despite good recovery from the hemorrhage. They focused on both male and female patients to assess differences in sexual dysfunction. The motivation came from the lack of data on this specific aspect of recovery. By using standardized questionnaires, the researchers sought to quantify the prevalence of sexual dysfunction. They also aimed to identify factors associated with changes in sexual pleasure. This approach allowed for a comprehensive assessment of post-hemorrhage sexual health. The findings could inform future clinical guidelines and patient follow-up protocols.
Main Methods:
The study used anonymous, standardized questionnaires to collect data on sexual function. Participants included 33 patients treated between 2005 and 2013 at the Cantonal Hospital St Gallen. All patients had favorable neurologic outcomes based on the Glasgow Outcome Scale. The researchers employed the IIEF and FSFI questionnaires to assess male and female sexual function. A statement on subjective changes in sexual pleasure after aSAH was also included. The data collection period spanned eight years, allowing for a longitudinal view. The study compared patients with WFNS grade 1 and grade 2 aSAH. Statistical analysis was used to determine associations between hemorrhage severity and sexual dysfunction.
Main Results:
Ten of the 33 patients reported a subjective worsening of sexual pleasure after aSAH. Among the 19 female patients, nine met FSFI criteria for sexual dysfunction. All 19 women had hypoactive sexual desire disorder according to the FSFI. Erectile dysfunction was reported by seven of the 14 male patients. The prevalence of sexual dysfunction in women was 47.4%, and in men, it was 50%. Patients with WFNS grade 2 aSAH were more likely to report a decline in sexual pleasure. The Glasgow Outcome Scale scores were all 4 or 5, indicating favorable neurologic outcomes. These findings suggest that sexual dysfunction is common despite good recovery from aSAH.
Conclusions:
The study confirms that sexual dysfunction is common in patients with favorable neurologic outcomes after aSAH. The findings suggest that even with good recovery, sexual pleasure may be affected. The researchers propose that sexual health should be considered in follow-up care for these patients. The data indicate that both men and women experience significant sexual dysfunction. The association between WFNS grade and sexual dysfunction highlights the importance of hemorrhage severity. The authors emphasize the need for further research into the mechanisms behind these effects. They suggest that clinicians should routinely assess sexual function in post-aSAH patients. These conclusions are based on the specific data collected in this study.
Frequently Asked Questions
The study found that 31.3% of patients with favorable neurologic outcomes reported a subjective worsening of sexual pleasure after aSAH.
The researchers used the International Index of Erectile Function (IIEF) and Female Sexual Function Index (FSFI) questionnaires to assess sexual function.
The Glasgow Outcome Scale score indicates favorable neurologic recovery, allowing the study to focus on sexual dysfunction independent of other neurological deficits.
Patients with WFNS grade 2 aSAH were significantly more likely to report a decline in sexual pleasure compared to those with WFNS grade 1.
All 19 female patients in the study had hypoactive sexual desire disorder according to the FSFI criteria.
The authors propose that sexual health should be explored during follow-up with patients who have favorable neurologic outcomes after aSAH.
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