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Related Concept Videos

Properties of Transition Metals02:58

Properties of Transition Metals

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Transition metals are defined as those elements that have partially filled d orbitals. As shown in Figure 1, the d-block elements in groups 3–12 are transition elements. The f-block elements, also called inner transition metals (the lanthanides and actinides), also meet this criterion because the d orbital is partially occupied before the f orbitals.
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Socioemotional Development during Infancy01:30

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Socio-emotional development in infancy is primarily shaped by early emotional responses and social connections, with temperament playing a central role. Temperament refers to the consistent patterns in an individual's emotional and behavioral responses, observable even in infancy. By examining temperament, researchers can better understand an infant's unique ways of interacting with the world, influencing subsequent personality and socio-emotional growth.
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Phase Transitions02:31

Phase Transitions

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Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
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Phase Transitions: Melting and Freezing02:39

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Heating a crystalline solid increases the average energy of its atoms, molecules, or ions, and the solid gets hotter. At some point, the added energy becomes large enough to partially overcome the forces holding the molecules or ions of the solid in their fixed positions, and the solid begins the process of transitioning to the liquid state or melting. At this point, the temperature of the solid stops rising, despite the continual input of heat, and it remains constant until all of the solid is...
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Phase Transitions: Sublimation and Deposition02:33

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Some solids can transition directly into the gaseous state, bypassing the liquid state, via a process known as sublimation. At room temperature and standard pressure, a piece of dry ice (solid CO2) sublimes, appearing to gradually disappear without ever forming any liquid. Snow and ice sublimate at temperatures below the melting point of water, a slow process that may be accelerated by winds and the reduced atmospheric pressures at high altitudes. When solid iodine is warmed, the solid sublimes...
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Mismatch Repair01:36

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Related Experiment Video

Updated: Feb 16, 2026

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
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Symptomatic partial and transitional atrioventricular septal defect repaired in infancy.

Sylvia Krupickova1, Gareth J Morgan2, Mun Hong Cheang3

  • 1Department of Paediatric Cardiology, Royal Brompton Hospital, London, UK.

Heart (British Cardiac Society)
|December 31, 2017
PubMed
Summary

Infants with symptomatic atrioventricular septal defects need early surgical repair. Unfavorable left atrioventricular valve anatomy is a key risk factor for reoperation in these young patients.

Keywords:
congenital heart diseasecongenital heart disease surgery

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Area of Science:

  • Pediatric Cardiology
  • Congenital Heart Disease Surgery
  • Pediatric Cardiac Surgery

Background:

  • Symptomatic infants with partial and transitional atrioventricular septal defects (AVSD) undergoing early surgical repair are considered high-risk.
  • The specific outcomes and risk factors for this patient group are not well-defined.

Purpose of the Study:

  • To evaluate the outcomes of symptomatic infants undergoing early surgical repair for partial and transitional AVSD.
  • To identify risk factors associated with mortality and reoperation in this cohort.

Main Methods:

  • A multicenter study involving 51 infants (0-1 year) with symptomatic partial/transitional AVSD requiring biventricular repair.
  • Data collected on patient demographics, surgical procedures, valve anatomy, and clinical outcomes including mortality and reoperation rates.

Main Results:

  • Three in-hospital deaths (5.9%) occurred post-primary repair.
  • Eleven patients (22%) required reoperation, primarily for left atrioventricular valve regurgitation/stenosis.
  • Unfavorable left atrioventricular valve anatomy was the sole predictor of reoperation (31% of patients had unfavorable anatomy).

Conclusions:

  • Early surgical repair of symptomatic partial/transitional AVSD in infants leads to significant morbidity and mortality.
  • A high reoperation rate is associated with unfavorable left atrioventricular valve anatomy in this population.