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Updated: Feb 16, 2026

Impact Assessment of Repeated Exposure of Organotypic 3D Bronchial and Nasal Tissue Culture Models to Whole Cigarette Smoke
Published on: February 12, 2015
Impacts of fire smoke plumes on regional air quality, 2006-2013
Alexandra E Larsen1, Brian J Reich1, Mark Ruminski2
1Department of Statistics, North Carolina State University, Raleigh, NC, USA.
Abstract:
Increases in the severity and frequency of large fires necessitate improved understanding of the influence of smoke on air quality and public health. The objective of this study is to estimate the effect of smoke from fires across the continental U.S. on regional air quality over an extended period of time. We use 2006-2013 data on ozone (O3), fine particulate matter (PM2.5), and PM2.5 constituents from environmental monitoring sites to characterize regional air quality and satellite imagery data to identify plumes. Unhealthy levels of O3 and PM2.5 were, respectively, 3.3 and 2.5 times more likely to occur on plume days than on clear days. With a two-stage approach, we estimated the effect of plumes on pollutants, controlling for season, temperature, and within-site and between-site variability. Plumes were associated with an average increase of 2.6 p.p.b. (2.5, 2.7) in O3 and 2.9 µg/m3 (2.8, 3.0) in PM2.5 nationwide, but the magnitude of effects varied by location. The largest impacts were observed across the southeast. High impacts on O3 were also observed in densely populated urban areas at large distance from the fires throughout the southeast. Fire smoke substantially affects regional air quality and accounts for a disproportionate number of unhealthy days.
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