Related Experiment Video
Updated: Feb 16, 2026

Open Tracheostomy Gastric Acid Aspiration Murine Model of Acute Lung Injury Results in Maximal Acute Nonlethal Lung Injury
Published on: February 26, 2017
Pulmonary Endothelial Cell Apoptosis in Emphysema and Acute Lung Injury
Eboni Chambers1,2, Sharon Rounds1,2, Qing Lu3,4
1Department of Medicine, Alpert Medical School of Brown University, Providence, RI, USA.
Abstract:
Apoptosis plays an essential role in homeostasis and pathogenesis of a variety of human diseases. Endothelial cells are exposed to various environmental and internal stress and endothelial apoptosis is a pathophysiological consequence of these stimuli. Pulmonary endothelial cell apoptosis initiates or contributes to progression of a number of lung diseases. This chapter will focus on the current understanding of the role of pulmonary endothelial cell apoptosis in the development of emphysema and acute lung injury (ALI) and the factors controlling pulmonary endothelial life and death.
Related Concept Videos
Acute Kidney Injury I: Introduction
Acute Kidney Injury II: Pathophysiology
Lung Capacity
Acute Kidney Injury VI: Nursing Management
Apoptosis
Acute Kidney Injury V: Interprofessional Care

