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Updated: Feb 16, 2026

Pretreatment of Lignocellulosic Biomass with Low-cost Ionic Liquids
Published on: August 10, 2016
One-pot bioprocess for lactic acid production from lignocellulosic agro-wastes by using ionic liquid stable
1Enzyme and Microbial Biochemistry Laboratory, Department of Chemistry, Indian Institute of Technology Delhi, Hauz Khas, New Delhi 110016, India.
Abstract:
The lignocellulosic agro-wastes are an attractive renewable resource in biorefinery for production of value-added platform chemicals and biofuels. The study describes use of different agro-wastes as substrate for production of lactic acid, a C3-platform chemical and high demand industrial product by Lactobacillus brevis in a one-pot bioprocess. The simultaneous saccharification and co-fermentation (SSCF) process was achieved by L. brevis governed fermentation of sugars, derived from saccharification of ionic liquid pretreated feedstocks by nanoimmobilized cellulase, which was further recovered and used for consecutive cycle. The lactic acid yields of 0.22, 0.49, 0.52 g/g were obtained from cottonseed cake, wheat straw and sugarcane bagasse, respectively. The ionic liquid-tolerant L. brevis, cellulolytic reusable nanoimmobilized enzyme coupled with valorization of renewable feedstocks points towards a holistic approach for future biorefineries with sustainable production of bioproducts.
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