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Updated: Feb 16, 2026
CMAP Scan MUNE MScan - A Novel Motor Unit Number Estimation MUNE Method
Published on: June 7, 2018
Correlations between MUNIX and adapted multiple point stimulation MUNE methods
Karim Benmouna1, Christophe Milants1, François Charles Wang1
1Department of Neurophysiology, CHU Sart Tilman B35, 4000 Liège, Belgium.
Objective:
The aim of this study was to evaluate how the motor unit number index (MUNIX) is related to the adapted multiple point stimulation (AMPS) technique.
Methods:
MUNIX and AMPS technique were prospectively performed on thenar muscles in 20 consecutive patients referred to our neurophysiological laboratory with the clinical diagnosis of a possible motoneurone disorder (MND). The clinical and paraclinical assessment confirmed the diagnosis of MND in 13 out of 20 patients, amyotrophic lateral sclerosis (ALS) in 9 (with MND group). In the other 7 patients, there were neither evidence of MND, nor of any peripheral nervous system disease (without MND group).
Results:
AMPS and MUNIX data were significantly (p < 0.001) lower in patients with MND than in patients without MND. There was a strong significant positive linear correlation between AMPS and MUNIX values (n = 20; R = 0.83; p < 0.01).
Conclusion:
Both MUNIX and AMPS methods could serve as a reliable marker to document the motor unit loss.
Significance:
The present paper constitutes one more clue of MUNIX reliability.
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