Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Observations on vascular neuropathies.

H Urich

    Clinical and Experimental Neurology
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    This study investigated obliterative vascular disease in 13 autopsy cases, finding necrotizing lesions in most, supporting polyarteritis nodosa as a reaction pattern. Rheumatoid neuropathy is primarily caused by occlusive vascular disease.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The remote effects of cancer on the nervous system.

    Proceedings of the Royal Society of Medicine·2010
    Same author

    Cerebellar hypoplasia with heterotopic purkinje cells in the molecular layer and preservation of the granule layers associated with severe encephalopathy. A new entity?

    Neuropediatrics·2003
    Same author

    Lethal X-linked microcephaly with dysmorphic features, bilateral optic pathway aplasia and normal eyes.

    Acta neuropathologica·2001
    Same author

    alpha-Lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria.

    Free radical biology & medicine·1999
    Same author

    The mysterious prion diseases--a historical perspective.

    Materia medica Polona. Polish journal of medicine and pharmacy·1996
    Same author

    Calbindin-D28k in subsets of medulloblastomas and in the human medulloblastoma cell line D283 Med.

    Archives of pathology & laboratory medicine·1995
    Same journal

    Alzheimer's disease and Alzheimer-type of cerebral degenerations in Chinese.

    Clinical and experimental neurology·1994
    Same journal

    Primary cerebral abscess due to Nocardia asteroides presenting as stroke.

    Clinical and experimental neurology·1994
    Same journal

    Rhinocerebral mucormycosis presenting as periorbital cellulitis with blindness: report of 2 cases.

    Clinical and experimental neurology·1994
    Same journal

    Routine use of lamotrigine, a new anti-epileptic medication, and the value of measuring its blood levels.

    Clinical and experimental neurology·1994
    Same journal

    Isaac's syndrome: report of a case responding to valproic acid.

    Clinical and experimental neurology·1994
    Same journal

    Huntington's disease in Hong Kong Chinese: epidemiology and clinical picture.

    Clinical and experimental neurology·1994
    See all related articles

    Area of Science:

    • Neuropathology
    • Rheumatology
    • Vascular Pathology

    Background:

    • Obliterative vascular disease affects the vasa nervorum in various systemic conditions.
    • Rheumatoid neuropathy is a known complication of rheumatoid arthritis.

    Purpose of the Study:

    • To investigate the pathological basis of rheumatoid neuropathy.
    • To determine the role of vascular disease in rheumatoid neuropathy.

    Main Methods:

    • Autopsy studies of 13 cases with obliterative vascular disease.
    • Examination of lesions including necrotizing arteritis and Bywater's arteritis.
    • Comparison with clinical data and sural nerve biopsy findings.

    Main Results:

    • Necrotizing lesions of the vasa nervorum were observed in most cases.

    Related Experiment Videos

  • Rheumatoid neuropathy cases showed either necrotizing arteritis or bland endarteritis (Bywater's arteritis).
  • Occlusive vascular disease was implicated in severe and most mild rheumatoid neuropathy cases.

    • Conclusions:

    • Rheumatoid neuropathy is predominantly caused by occlusive vascular disease of the vasa nervorum.
    • Polyarteritis nodosa may represent a common reaction pattern rather than a distinct entity.
    • Segmental demyelination, independent of vascular lesions, can contribute to mild neuropathy.