Related Experiment Video
Updated: Feb 16, 2026

Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software
Published on: October 30, 2018
Increased local connectivity of brain functional networks during facial processing in schizophrenia: evidence from
Tianyi Yan1,2, Wenhui Wang1,2, Tiantian Liu1,2
1School of Life Science, Beijing Institute of Technology, Beijing, China.
Abstract:
Schizophrenia is often considered to be a disconnection syndrome. The abnormal interactions between large-scale functional brain networks result in cognitive and perceptual deficits. The present study investigated event-related functional connectivity networks to compare facial processing in individuals with and without schizophrenia. Faces and tables were presented to participants, and event-related phase synchrony, represented by the phase lag index (PLI), was calculated. In addition, cortical oscillatory dynamics may be useful for understanding the neural mechanisms underlying the disparate cognitive and functional impairments in schizophrenic patients. Therefore, the dynamic graph theoretical networks related to facial processing were compared between individuals with and without schizophrenia. Our results showed that event-related phase synchrony was significantly reduced in distributed networks, and normalized clustering coefficients were significantly increased in schizophrenic patients relative to those of the controls. The present data suggest that schizophrenic patients have specific alterations, indicated by increased local connectivity in gamma oscillations during facial processing.
Related Concept Videos
Increasing Function
The Evidence for Evolution
Functions of Connective Tissues
Hard connective tissues, such as bones and cartilage, provide structure and support to the body.
Network Function of a Circuit
Schizophrenia
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...

