Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gas movement during jet ventilation.

J D Young1

  • 1Nuffield Department of Anaesthetics, Radcliffe Infirmary, Oxford, UK.

Acta Anaesthesiologica Scandinavica. Supplementum
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The natural history of epiphora in childhood.

Eye (London, England)·1998
Same author

Effect of L-lysine on nitric oxide production in ovine endotoxaemia.

British journal of anaesthesia·1998
Same author

Demonstration of equilibrative nucleoside transporters (hENT1 and hENT2) in nuclear envelopes of cultured human choriocarcinoma (BeWo) cells by functional reconstitution in proteoliposomes.

The Journal of biological chemistry·1998
Same author

Conductimetry for enzyme teaching.

Biochemical Society transactions·1998
Same author

Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines.

Cancer research·1998
Same author

Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs.

The Journal of biological chemistry·1998

Measuring expiratory flows during jet ventilation in dogs revealed that tidal volume decreased and minute volume increased with higher respiratory rates. These findings support a convective gas movement model.

Area of Science:

  • Mechanical Ventilation
  • Respiratory Physiology
  • Fluid Dynamics

Background:

  • Jet ventilation is a specialized mechanical ventilation technique.
  • Understanding gas dynamics during high-frequency ventilation is crucial for patient management.
  • Previous models have not fully elucidated volume changes at varying respiratory rates.

Purpose of the Study:

  • To investigate the measurement of tidal, entrained, and spilt volumes during jet ventilation.
  • To analyze the impact of increasing respiratory rate on these volumes in a canine model.
  • To evaluate the compatibility of observed changes with a convective gas movement model.

Main Methods:

  • Utilized a bias flow circuit to examine expiratory limb flows.
  • Measured tidal, entrained, and spilt volumes during mechanical ventilation in a canine model.

Related Experiment Videos

  • Systematically increased respiratory rate from 12 to 200 breaths/min.
  • Main Results:

    • Tidal volume decreased as respiratory rate increased.
    • Minute volume increased with rising respiratory rate.
    • Entrained volume remained a constant fraction of tidal volume.
    • Spilt volume decreased as a fraction of jet volume at higher respiratory rates.

    Conclusions:

    • The observed volume changes are consistent with a convective model of gas movement during jet ventilation.
    • Respiratory rate significantly influences volume dynamics in this ventilation mode.
    • This measurement method provides insights into gas distribution and efficiency during high-frequency jet ventilation.