Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Autistic behaviour in Moebius syndrome.

C Gillberg1, S Steffenburg

  • 1Department of Child and Adolescent Psychiatry, University of Göteborg, Sweden.

Acta Paediatrica Scandinavica
|March 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Regulatory Problems in Infancy: Prevalence and Association With Early Neurodevelopmental and Medical Conditions in Toddlers.

Acta paediatrica (Oslo, Norway : 1992)·2025
Same author

22q11.2 Deletion Syndrome: Cognitive, Visuomotor, and Adaptive Functioning Followed Longitudinally.

Brain and behavior·2025
Same author

Cognitive functioning in adult psychiatric patients with and without attention-deficit/hyperactivity disorder.

Brain and behavior·2024
Same author

Children born to parents with mild intellectual disability: Register-based follow-up of psychiatric and neurodevelopmental diagnoses and out-of-home placements.

Acta paediatrica (Oslo, Norway : 1992)·2024
Same author

Long-term medication for ADHD (LMA) trial: 2-year prospective observational study in children and adolescents. Core symptoms, daily functioning, and comorbidity outcomes.

European archives of psychiatry and clinical neuroscience·2024
Same author

Adult psychiatric and psychosocial outcomes of children with mild intellectual disability: a register follow-up of a population-based cohort.

Journal of intellectual disability research : JIDR·2023
Same journal

Atrial natriuretic peptide and renin-aldosterone relationship in healthy newborn infants.

Acta paediatrica Scandinavica·1991
Same journal

Adult panhypopituritarism presenting as idiopathic growth hormone deficiency in childhood: really idiopathic?

Acta paediatrica Scandinavica·1991
Same journal

Growth hormone therapy and final height in girls with Turner's syndrome.

Acta paediatrica Scandinavica·1991
Same journal

Mineral metabolism in obese children.

Acta paediatrica Scandinavica·1991
Same journal

Sex differences in vulnerability?

Acta paediatrica Scandinavica·1991
Same journal

Idiopathic dilatation of the aorta with dissection in a family without Marfan syndrome.

Acta paediatrica Scandinavica·1991
See all related articles

Autism symptoms are common in Moebius syndrome, with 40% of patients showing signs. This suggests a potential shared neurobiological cause affecting the brainstem in both Moebius syndrome and autistic disorder.

Area of Science:

  • Neuroscience
  • Developmental Pediatrics
  • Genetics

Background:

  • Moebius syndrome is a rare congenital neurological disorder.
  • Autistic disorder is a neurodevelopmental condition characterized by social and communication deficits.

Purpose of the Study:

  • To investigate the prevalence of autistic disorder symptoms in individuals with Moebius syndrome.
  • To explore potential shared neurobiological underpinnings between Moebius syndrome and autistic disorder.

Main Methods:

  • A cohort of 17 children and young adults diagnosed with Moebius syndrome was assessed.
  • Clinical evaluation for symptoms characteristic of autistic disorder was performed.

Main Results:

  • Approximately 40% of the participants exhibited all or many symptoms of autistic disorder.

Related Experiment Videos

  • The observed frequency of autistic symptoms in Moebius syndrome is notably high.

    • Conclusions:

    • There is a significant co-occurrence of autistic disorder symptoms in Moebius syndrome.
    • This high frequency suggests a potential common neurobiological deficit, possibly at the brainstem level, underlying both conditions.