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Related Concept Videos

Mismatch Repair01:36

Mismatch Repair

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Overview
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Mismatch Repair01:20

Mismatch Repair

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Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...
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Types of Errors: Detection and Minimization01:12

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Error is the deviation of the obtained result from the true, expected value or the estimated central value. Errors are expressed in absolute or relative terms.
Absolute error in a measurement is the numerical difference from the true or central value. Relative error is the ratio between absolute error and the true or central value, expressed as a percentage.
Errors can be classified by source, magnitude, and sign. There are three types of errors: systematic, random, and gross.
Systematic or...
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Genome Copying Errors02:46

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DNA replication is a well-evolved process that copies millions of base pairs with high fidelity during each cell division. Occasionally a wrong base or a long stretch of wrong bases may get added to the daughter strands. If the errors are left unchecked, cells might accumulate several mutations that might endanger their  survival. Therefore, the copying errors are checked and repaired at three levels.
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Gene Duplication and Divergence02:37

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The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was  generated by gene duplication and divergence, indicating its critical role in evolution.
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Overview of Transposition and Recombination02:13

Overview of Transposition and Recombination

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Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
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Determining the Role of Maternally-Expressed Genes in Early Development with Maternal Crispants
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Correction: Equivalent Indels - Ambiguous Functional Classes and Redundancy in Databases.

Jens Assmus, Jürgen Kleffe, Armin O Schmitt

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    Summary
    This summary is machine-generated.

    This study corrects a previously published article DOI. The correction ensures accurate citation and retrieval of scientific research. Researchers should use the updated DOI for all future references.

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    Area of Science:

    • Scientific publishing
    • Bibliometrics
    • Scholarly communication

    Background:

    • Accurate citation is crucial for scientific integrity.
    • Digital Object Identifiers (DOIs) ensure reliable access to research.
    • Errors in DOIs can hinder research dissemination and impact.

    Purpose of the Study:

    • To correct an erroneous Digital Object Identifier (DOI) for a published article.
    • To ensure proper attribution and accessibility of scientific work.
    • To maintain the integrity of the scientific record.

    Main Methods:

    • Identifying the incorrect DOI in the original publication.
    • Verifying the correct DOI through publisher records.
    • Issuing a correction notice with the accurate DOI.

    Main Results:

    • The incorrect DOI associated with the article has been identified.
    • A correction notice has been published to rectify the error.
    • The accurate DOI is now available for citation.

    Conclusions:

    • The correction of the DOI ensures that the article is correctly discoverable.
    • Accurate metadata is essential for the effective functioning of scholarly communication systems.
    • This correction upholds the principles of scientific accuracy and transparency.