Related Experiment Video
Updated: Feb 16, 2026

Intranasal Administration of CNS Therapeutics to Awake Mice
Published on: April 8, 2013
Administration of Gonadotropins for Superovulation in Mice
Abstract:
For experiments that require large numbers of preimplantation mouse embryos, such as microinjection of zygotes, gonadotropins are administered to females before mating to increase the number of oocytes that are ovulated (i.e., to induce superovulation). Pregnant mare serum gonadotropin (PMSG) is used to mimic the oocyte maturation effect of the endogenous follicle-stimulating hormone (FSH), and human chorionic gonadotropin (hCG) is used to mimic the ovulation induction effect of luteinizing hormone (LH).
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