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Related Experiment Video

Updated: Feb 16, 2026

Clinical Practice Protocol of Creative Music Therapy for Preterm Infants and Their Parents in the Neonatal Intensive Care Unit
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When serendipity meets creativity.

Masaaki Yamamoto1

  • 1Katsuta Hospital Mito GammaHouse, Department of Neurosurgery, Hitachi-naka, Japan.

Journal of Radiosurgery and SBRT
|January 4, 2018
PubMed
Summary
This summary is machine-generated.

Established evidence evolves, even in randomized controlled trials. This review explores novel applications of gamma knife radiosurgery (GKRS) for brain metastases and meningiomas, challenging existing paradigms and inspiring future research.

Keywords:
arteriovenous malformationbenign brain tumorsbraingamma knifemetastatic brain tumorradiosurgery

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Area of Science:

  • Neurosurgery
  • Radiation Oncology

Background:

  • Established medical evidence is not static and can become outdated.
  • Randomized controlled trials, while rigorous, are subject to future challenges.
  • Innovation in medical practice often requires creative thinking and serendipity.

Purpose of the Study:

  • To review key cases from a two-decade career in gamma knife radiosurgery (GKRS).
  • To highlight instances that led to the initiation of new clinical trials.
  • To inspire novel research directions in radiosurgery among peers.

Main Methods:

  • Retrospective review of pivotal cases in gamma knife radiosurgery (GKRS).
  • Description of novel GKRS applications and modified techniques.
  • Focus on challenging established treatment paradigms.

Main Results:

  • Initiation of trials for GKRS in multiple brain metastases.
  • Development of two-stage GKRS for large arteriovenous malformations.
  • Exploration of GKRS for complex meningiomas and radiosurgical thrombolization.
  • Investigation of pre-operative GKRS for large brain metastases.

Conclusions:

  • GKRS has evolved beyond initial applications, demonstrating versatility.
  • Specific case observations can drive significant advancements in treatment protocols.
  • Continued innovation in radiosurgery is crucial for patient care.