Related Experiment Video
Updated: Feb 16, 2026

Quantification of Protein Interaction Network Dynamics using Multiplexed Co-Immunoprecipitation
Published on: August 21, 2019
Agents and networks to model the dynamic interactions of intracellular transport
Luis S Mayorga1, Meghna Verma2, Raquel Hontecillas2
1IHEM (Universidad Nacional de Cuyo, CONICET), Facultad de Ciencias Médicas, Facultad de Ciencias Exactas y Naturales, Mendoza, Argentina.
Abstract:
Cell biology is increasingly evolving to become a more formal and quantitative science. The field of intracellular transport is no exception. However, it is extremely challenging to formulate mathematical and computational models for processes that involve dynamic structures that continuously change their shape, position and composition, leading to information transfer and functional outcomes. The two major strategies employed to represent intracellular trafficking are based on "ordinary differential equations" and "agent-" based modeling. Both approaches have advantages and drawbacks. Combinations of both modeling strategies have promising characteristics to generate meaningful simulations for intracellular transport and allow the formulation of new hypotheses and provide new insights. In the near future, cell biologists will encounter and hopefully overcome the challenge of translating descriptive cartoon representations of biological systems into mathematical network models.
More Related Videos
10:44Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
Published on: December 7, 2021
07:35Immobilization of Caenorhabditis elegans to Analyze Intracellular Transport in Neurons
Published on: October 18, 2017
Related Concept Videos
Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
Primary Active Transport
Intracellular Signaling Cascades
Facilitated Transport
Network Covalent Solids
To break or to melt a covalent network solid, covalent bonds must be broken. Because covalent bonds are relatively strong, covalent network solids are typically...
Secondary Active Transport