Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Complex segregation analysis of dental morphological variants.

C R Nichol1

  • 1Department of Anthropology, Arizona State University, Tempe 85287.

American Journal of Physical Anthropology
|January 1, 1989
PubMed
Summary

Complex segregation analysis suggests major genes influence 13 dental traits. However, a significant environmental role in dental crown morphology is also indicated, with a mean transmissibility of 0.36.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intra- and interobserver concordance in classifying dental morphology.

American journal of physical anthropology·1986
Same author

Variation in the convexity of the human maxillary incisor labial surface.

American journal of physical anthropology·1984
See all related articles

Area of Science:

  • Anthropology
  • Genetics
  • Dentistry

Background:

  • Understanding the inheritance patterns of dental morphology is crucial for evolutionary and clinical studies.
  • Dental crown morphology and jaw characteristics exhibit significant variation within human populations.

Purpose of the Study:

  • To investigate the probable mode of inheritance for 20 dental crown morphological variants and four jaw characteristics.
  • To differentiate between major gene effects and polygenic inheritance in dental traits.

Main Methods:

  • Employed complex segregation analysis using the method of Morton et al. (1971).
  • Tested single-locus models (dominant, codominant, recessive) and an additive polygenic model.
  • Utilized maximum likelihood estimation for transmissibility and analyzed traits using ordinal scales and dichotomies.

Main Results:

  • Identified probable major gene influence for 13 out of 24 examined dental and jaw traits.
  • Found strong evidence for polygenic inheritance in two traits.
  • Nine traits lacked definitive conclusions due to methodological challenges.

Conclusions:

  • Suggests a significant role for major genes in the inheritance of specific dental morphological traits.
  • Indicates a substantial environmental contribution to dental crown morphology, with a mean transmissibility of 0.36.
  • Highlights potential challenges in trait classification affecting environmental influence estimations.

Related Experiment Videos