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Updated: Feb 16, 2026

Derivation of a Human Brain Organoid with Microglia Development
Published on: January 17, 2025
Organoids required! A new path to understanding human brain development and disease
1Department of Stem Cell and Regenerative Biology, Harvard University.
Abstract:
Our ability to study the developing human brain has recently been dramatically advanced by the development of human 'brain organoids', three-dimensional culture systems that recapitulate selected aspects of human brain development in reductionist, yet complex, tissues in vitro. Here I discuss the promises and challenges this new model system presents.
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