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Related Experiment Videos

Perforated typhoid enteritis: operative experience with 108 cases.

D E Meier1, O O Imediegwu, J L Tarpley

  • 1Department of Surgery, Baptist Medical Centre, Ogbomoso, Nigeria.

American Journal of Surgery
|April 1, 1989
PubMed
Summary

Surgical intervention for perforated typhoid enteritis has a high mortality rate, primarily due to sepsis. Prevention through safe water and sanitation is crucial for improving survival in this serious condition.

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Area of Science:

  • Medicine
  • Infectious Diseases
  • Surgical Gastroenterology

Background:

  • Typhoid enteritis perforation is a severe complication of Salmonella Typhi infection.
  • Operative management is often required but associated with significant mortality.

Purpose of the Study:

  • To review outcomes of surgical management for perforated typhoid enteritis.
  • To identify factors influencing survival and mortality.

Main Methods:

  • Retrospective review of 108 patients with perforated typhoid enteritis.
  • Analysis of surgical procedures, postoperative complications, and mortality.

Main Results:

  • High mortality rate (32%) primarily due to overwhelming sepsis.

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  • Common postoperative morbidities included intraabdominal abscess and wound dehiscence.
  • Surgical intervention included debridement and two-layer bowel closure in most patients.

    • Conclusions:

    • Improved survival hinges on preventing typhoid fever through safe water and sanitation, not solely on surgical advancements.
    • Aggressive operative management and antibiotics were insufficient to overcome sepsis in many cases.