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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Initiation of Translation02:33

Initiation of Translation

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Initiating translation is complex because it involves multiple molecules. Initiator tRNA, ribosomal subunits, and eukaryotic initiation factors (eIFs) are all required to assemble on the initiation codon of mRNA. This process consists of several steps that are mediated by different eIFs.
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Beams01:30

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Beams are integral components of structural engineering and construction, designed to support loads applied at various points along their length. These long, straight members can be classified based on geometry, cross-section, support type, and equilibrium condition.
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Initiation is the first step of transcription in eukaryotes. Prokaryotic RNA Polymerase (RNAP) can bind to the template DNA and start transcribing. On the other hand, transcription in eukaryotes requires additional proteins, called transcription factors, to first bind to the promoter region in the DNA template. This binding helps recruit the specific RNAP that can assemble on the DNA and start transcription.
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Fast acquisition cone-beam computed tomography: initial experience with a 10 s protocol.

Visish M Srinivasan1, Gouthami Chintalapani2, Kevin Matthew Camstra1

  • 1Department of Neurosurgery, Baylor College of Medicine, Houston, Texas, USA.

Journal of Neurointerventional Surgery
|January 5, 2018
PubMed
Summary

A new 10-second Cone-beam CT (CBCT) protocol provides fast, high-quality neurovascular device imaging. This rapid CBCT technique ensures diagnostic image quality for evaluating implanted devices in patients, even those who are awake.

Keywords:
angiographyflow diverterstent

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Area of Science:

  • Medical Imaging
  • Radiology
  • Neuroendovascular Therapy

Background:

  • Cone-beam computed tomography (CBCT) is crucial for cross-sectional imaging in angiography suites.
  • Applications include evaluating implanted devices and localizing cerebrovascular lesions.
  • A novel, faster CBCT acquisition protocol is presented for neurovascular device imaging.

Purpose of the Study:

  • To present and validate the clinical utility of an alternative fast CBCT acquisition protocol.
  • To assess the feasibility of a 10-second CBCT protocol for neurovascular device imaging.
  • To compare image quality and diagnostic performance against a standard 20-second protocol.

Main Methods:

  • A new 10-second contrast-enhanced (CE)-CBCT protocol was tested in phantom, swine, and patient models.
  • Fewer projections (250 vs. 500) were used in the 10-second protocol compared to the 20-second protocol.
  • Image quality was assessed quantitatively in phantoms and qualitatively by blinded reviewers for device visibility and apposition.

Main Results:

  • 10-second CBCT images were comparable to 20-second images in phantom and animal studies.
  • Blinded reviewers successfully discerned flow diverter struts and assessed apposition in all 25 patient images.
  • The 10-second protocol achieved an average diagnostic quality rating of 4.28/5, with similar contrast and spatial resolution to the 20-second protocol.

Conclusions:

  • Neurovascular device imaging is feasible with a 10-second CBCT acquisition protocol.
  • The faster acquisition allows use in awake patients.
  • The 10-second protocol offers reduced radiation and contrast dose, enhancing patient safety.