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Published on: January 7, 2019
Aerobic anti-gravity exercise in patients with Charcot-Marie-Tooth disease types 1A and X: A pilot study
Kirsten L Knak1, Linda K Andersen1, John Vissing1
1Copenhagen Neuromuscular Center Department of Neurology Rigshospitalet University of Copenhagen Copenhagen Denmark.
Background:
Charcot-Marie-Tooth (CMT) disease is a hereditary neuropathy associated with impaired walking capacity. Some patients are too weak in the lower extremity muscles to walk at gravity with sufficient intensity or duration to gain benefit.
Aim:
The aim was to investigate the effect of aerobic anti-gravity exercise in weak patients with CMT 1A and X.
Methods:
Five adult patients performed moderate-intensity aerobic anti-gravity exercise 3/week for 10 weeks.
Results:
There was a significant positive difference in Berg balance scale and postural stability test between test occasions, and walking distance in the 6-min walk test trended to increase.
Conclusions:
The study indicates that the anti-gravity treadmill training of patients with CMT should be pursued in larger CMT cohorts.
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