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Dry Eye Assessment in Patients With Vitiligo
Sevil Karaman Erdur, Rukiye Aydin, Ali Balevi1
1Dermatology, School of Medicine, Istanbul Medipol University, Istanbul, Turkey.
Cornea
|January 5, 2018
Summary
Vitiligo is linked to higher tear osmolarity and impaired tear film function, increasing dry eye risk, especially with periocular involvement. This study evaluated tear film parameters in vitiligo patients.
Area of Science:
- Ophthalmology
- Dermatology
- Ocular Surface Disease
Background:
- Vitiligo, a depigmentation disorder, can affect ocular structures.
- Ocular surface health is crucial for visual comfort and function.
Purpose of the Study:
- To investigate tear osmolarity and tear film parameters in patients with vitiligo.
- To compare ocular surface findings between vitiligo patients with and without periocular involvement and healthy controls.
Main Methods:
- Evaluated 25 eyes of vitiligo patients with periocular involvement, 30 eyes of vitiligo patients without periocular involvement, and 20 control eyes.
- Assessed tear osmolarity, Schirmer I test, tear film breakup time, ocular surface fluorescein staining, and Ocular Surface Disease Index (OSDI) questionnaire.
Main Results:
- Vitiligo patients exhibited significantly higher tear osmolarity and reduced tear film breakup time compared to controls.
- Ocular Surface Disease Index scores were significantly higher in vitiligo patients, indicating greater dry eye symptoms.
- No significant differences were found in Schirmer I test or fluorescein staining scores among the groups.
Conclusions:
- Vitiligo is associated with tear hyperosmolarity and tear film dysfunction.
- Patients with vitiligo, particularly those with periocular involvement, may be at increased risk for developing dry eye disease.
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