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Homogeneous Glycoconjugate Produced by Combined Unnatural Amino Acid Incorporation and Click-Chemistry for Vaccine Purposes
Published on: December 19, 2020
Recent Advances in the Chemistry of Glycoconjugate Amphiphiles
Laurent Latxague1, Alexandra Gaubert2, Philippe Barthélémy3
1ARNA Laboratory, Inserm U1212, CNRS UMR 5320, Université de Bordeaux, F-33000 Bordeaux, France. laurent.latxague@u-bordeaux.fr.
Abstract:
Glyconanoparticles essentially result from the (covalent or noncovalent) association of nanometer-scale objects with carbohydrates. Such glyconanoparticles can take many different forms and this mini review will focus only on soft materials (colloids, liposomes, gels etc.) with a special emphasis on glycolipid-derived nanomaterials and the chemistry involved for their synthesis. Also this contribution presents Low Molecular Weight Gels (LMWGs) stabilized by glycoconjugate amphiphiles. Such soft materials are likely to be of interest for different biomedical applications.
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