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Updated: Feb 16, 2026
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Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
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Oncoplastic breast conserving surgery with tailored needle-guided excision.
Fernando Hernanz1, Mónica González-Noriega1, Sonia Sánchez1
1Oncoplastic Breast Unit, Hospital Universitario Valdecilla, University of Cantabria, Santander, Spain.
Gland Surgery
|January 6, 2018
Summary
Oncoplastic breast conserving surgery (OBCS) combined with tailored wire-guided localization (WL) achieves good results for early breast cancer. This approach offers an acceptable rate of positive margins and a high rate of successful breast conserving surgery.
Area of Science:
- Surgical Oncology
- Breast Cancer Treatment
- Medical Devices
Background:
- Breast conserving surgery (BCS) with an oncoplastic approach (OBCS) is the standard for early breast cancer.
- Wire-guided localization (WL) is commonly used for tumor excision.
- Minimizing positive margins and re-excisions while improving cosmetic outcomes is a key goal.
Purpose of the Study:
- To evaluate the combination of OBCS and tailored WL for early breast cancer.
- To report on the experience with this combined surgical approach.
Main Methods:
- Retrospective study of 148 breast cancer patients treated between March 2013 and December 2015.
- Utilized OBCS with tailored WL, individualizing wire placement based on patient specifics.
- Multivariate analysis to identify associations between preoperative clinic-pathologic variables and margin status.
Main Results:
- The rate of positive margins was 13.5%.
- 10.8% of patients required re-intervention for oncologic reasons.
- Multifocality was significantly associated with involved margins (OR 4.67).
Conclusions:
- OBCS combined with tailored WL provides an acceptable rate of positive margins.
- This approach leads to a high rate of successful final breast conserving surgery.
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