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Transient Expression in Red Beet of a Biopharmaceutical Candidate Vaccine for Type-1 Diabetes
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Candidate for a live vaccine?
Justin Ralph Abbatemarco1, Alan Taege2
1Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Journal of Family Medicine and Primary Care
|January 6, 2018
Summary
End-stage liver disease patients may develop disseminated varicella-zoster virus (VZV) after receiving the Zostavax vaccine. This case highlights a potential risk for immunocompromised individuals awaiting liver transplantation.
Area of Science:
- Immunology
- Hepatology
- Vaccinology
Background:
- Immune dysfunction is common in end-stage liver disease (ESLD).
- The pretransplant period is crucial for optimizing vaccine protection before immunosuppression.
- The live varicella-zoster virus (VZV) vaccine, Zostavax, is recommended for ESLD patients.
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