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Candidate for a live vaccine?

Justin Ralph Abbatemarco1, Alan Taege2

  • 1Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

Journal of Family Medicine and Primary Care
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PubMed
Summary
This summary is machine-generated.

End-stage liver disease patients may develop disseminated varicella-zoster virus (VZV) after receiving the Zostavax vaccine. This case highlights a potential risk for immunocompromised individuals awaiting liver transplantation.

Area of Science:

  • Immunology
  • Hepatology
  • Vaccinology

Background:

  • Immune dysfunction is common in end-stage liver disease (ESLD).
Keywords:
Cirrhosis-associated immune deficiencyZostavax vaccinedisseminated cutaneous varicella zosterend-stage liver diseaseliver transplantation

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  • The pretransplant period is crucial for optimizing vaccine protection before immunosuppression.
  • The live varicella-zoster virus (VZV) vaccine, Zostavax, is recommended for ESLD patients.