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Imaging Studies I: CT and MRI

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Computed Tomography (CT) scan:
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How to focal boost in prostate cancer radiotherapy: ESTRO clinical practice consensus recommendations.

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Does Overall Treatment Time Impact Toxicity and Clinical Outcomes After Magnetic Resonance Imaging-Guided Stereotactic Body Radiotherapy to the Prostate? An evaluation of the Multi-OutcoMe EvaluatioN of radiation Therapy Using the MR-Linac Repository.

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Use of MRI-ultrasound Fusion to Achieve Targeted Prostate Biopsy
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[MRI-guided brachytherapy in prostate cancer].

M Peters1, M A Moerland, J L Noteboom

  • 1Universitair Medisch Centrum Utrecht, Cancer Center, afd. Radiotherapie, Utrecht.

Nederlands Tijdschrift Voor Geneeskunde
|January 6, 2018
PubMed
Summary

Focal salvage radiotherapy offers a targeted treatment for localized recurrent prostate cancer after initial radiation therapy. This approach aims to minimize side effects by precisely targeting the recurrent tumor within the prostate.

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Focal Laser Ablation of Prostate Cancer: An Office Procedure
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Area of Science:

  • Oncology
  • Radiation Oncology
  • Urology

Background:

  • Radiotherapy, including external beam and brachytherapy, is a common treatment for prostate cancer.
  • A subset of patients experience local recurrence after initial radiotherapy.
  • Historically, recurrent prostate cancer was managed with palliative hormonal therapy or whole-gland re-irradiation, often leading to significant adverse effects due to inadequate imaging for precise targeting.

Purpose of the Study:

  • To introduce and describe the technique of focal salvage radiotherapy for localized recurrent prostate cancer.
  • To highlight the advancements in imaging and radiotherapy that enable precise targeting of recurrent prostate cancer lesions.

Main Methods:

  • Focal salvage radiotherapy involves precise targeting of the localized recurrent tumor within the prostate.
  • Improvements in medical imaging (e.g., MRI, PET) allow for accurate delineation of recurrent lesions.
  • Advanced radiotherapy techniques enable dose escalation to the recurrent site while sparing surrounding tissues.

Main Results:

  • Focal salvage radiotherapy allows for treatment of localized recurrences previously managed with less precise methods.
  • This technique aims to improve treatment efficacy for recurrent prostate cancer.
  • Minimizing radiation dose to surrounding healthy tissues is a key benefit, potentially reducing toxicity.

Conclusions:

  • Focal salvage radiotherapy represents an advancement in managing recurrent prostate cancer.
  • Precise targeting of local recurrences can improve outcomes and reduce treatment-related morbidity.
  • Further research and clinical evaluation are warranted to establish the long-term efficacy and safety of this approach.