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A Multiple Integrated Social Stress Model for Psychiatric Disorders in Female C57BL/6J Mice
Published on: July 15, 2025
[Psychiatric disorders in epilepsy: clinical phenomena]
Anna Szucs1, Andras Horvath, Daniel Fabo
1Országos Klinikai Idegtudományi Intézet, Budapest, Hungary. szucsan@gmail.com.
Abstract:
The frequent psychiatric comorbidity in epilepsy compromises the quality of life of those affected, further increasing their suicide risk and the high burden of stigmatisation. Out of adulthood epilepsies, mesio-temporal lobe epilepsy carries the highest cognitive and psychiatric risk, making mental health comorbidities its inherent features. The pathomechanism of the epilepsy-related mental health symptoms and conditions appears to be related to undetected subclinical seizures, postictal exhaustion and inhibition, and the non-REM sleep related interictal epileptic activity. In our work we try to present some of the typical psychiatric syndromes and conditions seen in epilepsy. We aim to highlight the difficulties of treatment on the borderline of neurology and psychiatry.
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