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Oral features in patients with psoriasis: an observational study
Umberto Romeo1, Antonio Richetta2, Federica Rocchetti1
1Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Rome, Italy.
Minerva Stomatologica
|January 9, 2018
Summary
Psoriatic patients have a significantly higher prevalence of oral mucosal lesions, particularly geographic and fissured tongue, compared to healthy individuals. Further research is needed to understand the exact relationship between these oral conditions and psoriasis.
Area of Science:
- Dermatology
- Oral Medicine
- Immunology
Background:
- Psoriasis is a chronic inflammatory disease with potential systemic manifestations.
- Oral mucosal lesions are increasingly recognized as associated with psoriasis.
Purpose of the Study:
- To investigate and compare the prevalence of oral mucosal lesions in psoriatic patients versus healthy controls.
- To identify specific oral lesions strongly correlated with psoriasis.
Main Methods:
- An observational study involving 120 psoriatic patients and 201 healthy controls.
- Clinical examinations and specific diagnostic tools (e.g., panoramic X-ray, biopsies) were utilized.
- Statistical analysis using the chi-square test was performed to compare lesion prevalence.
Main Results:
- 78.34% of psoriatic patients exhibited oral manifestations, compared to 35.3% in the control group.
- Geographic tongue and fissured tongue showed a strong correlation with psoriasis.
- Other assessed conditions included periodontitis, temporomandibular joint disorders, and oral candidiasis.
Conclusions:
- Certain oral mucosal lesions, notably geographic and fissured tongue, are significantly associated with psoriasis.
- While not pathognomonic, these oral lesions warrant further investigation for their precise relationship with psoriasis.
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