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Updated: Feb 16, 2026

Ultrasonography in Experimental Reproductive Investigations on Rats
Published on: December 2, 2017
BRCA mutations and reproduction
Hagit Daum1, Tamar Peretz2, Neri Laufer3
1Department of Genetic and Metabolic Diseases, Hadassah Hebrew University Medical Center, Jerusalem, Israel.
Abstract:
Deleterious mutations in BRCA1 or BRCA2 genes have long been recognized as independent risk factors, mostly for breast and ovarian cancer. Numerous studies have evaluated the molecular processes involving these genes, the pathophysiology of BRCAness, follow up options and modes of prophylaxis. The fertility of BRCA carriers, however, has not been widely investigated. The aim of the present work is to review the literature pertaining to this issue.
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