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Hand preference in psychotic twins.

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  • 1Institute of Psychiatry, London, England.

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|January 15, 1989
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Summary
This summary is machine-generated.

This study investigated hand preference in twins with psychosis, finding no increased left-handedness in identical twins or those with psychosis. Results did not support a link between left-handedness and psychosis discordance.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Behavioral Genetics

Background:

  • Hand preference, specifically left-handedness, has been an area of interest in relation to functional psychosis.
  • Previous research suggested a potential link between non-right-handedness and psychosis, particularly in monozygotic twins.

Purpose of the Study:

  • To replicate a seminal study on hand preference in twins with functional psychosis.
  • To investigate whether left-handedness is more prevalent in monozygotic versus dizygotic twins with psychosis.
  • To examine the relationship between within-pair left-handedness and psychosis discordance in twin pairs.

Main Methods:

  • Examined hand preference for writing in 30 monozygotic (MZ) and 30 dizygotic (DZ) twin pairs.
  • Probands in these twin pairs had a history of functional psychosis.
  • Compared rates of left-handedness between MZ and DZ twins, and between psychotic and nonpsychotic individuals.

Main Results:

  • No increased rate of left-handedness was observed in MZ twins compared to DZ twins.
  • No higher prevalence of left-handedness was found in psychotic twins relative to nonpsychotic twins.
  • No association was identified between within-pair left-handedness and discordance for psychosis.

Conclusions:

  • The findings contradict previous reports suggesting a link between left-handedness and psychosis in twins.
  • The study did not find evidence supporting an association between non-right-handedness and psychosis or its discordance in twin pairs.
  • Reasons for the discrepancy with prior research are discussed, highlighting the need for further investigation into the etiology of psychosis and handedness.