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Fabrication of Mechanically Tunable and Bioactive Metal Scaffolds for Biomedical Applications
Published on: December 8, 2015
TPAOH assisted size-tunable Gd2O3@mSi core-shell nanostructures for multifunctional biomedical applications
E Pavitra1, G Seeta Rama Raju, Ganji Purnachandra Nagaraju
1Department of Biological Engineering, Biohybrid Systems Research Center (BSRC) Inha University, Incheon-22212, Republic of Korea. yunsuk.huh@inha.ac.kr.
Abstract:
We report a facile and large-scale synthesis of size-tunable and nontoxic mesoporous silica-coated Gd2O3:Eu3+ (Gd@mSi) core-shell nanostructures using a TPAOH assisted modified UHP technique. The role of TPAOH in controlling the particle size was evaluated. The potentiality of these Gd@mSi core-shell nanoparticles before and after folic acid conjugation was established by in vitro fluorescence microscopy of the U2OS cell lines for cancer imaging and therapy.
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