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Related Experiment Video

Updated: Feb 16, 2026

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
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HIV Infection: Antepartum Treatment and Management.

Helene B Bernstein1,2, Adam D Wegman2

  • 1Departments of Obstetrics and Gynecology.

Clinical Obstetrics and Gynecology
|January 9, 2018
PubMed
Summary
This summary is machine-generated.

Human immunodeficiency virus (HIV) management has evolved from a terminal illness to a chronic condition. Effective antiretroviral therapy now preserves maternal health and prevents mother-to-child HIV transmission during pregnancy.

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Area of Science:

  • Medicine
  • Virology
  • Public Health

Background:

  • Human immunodeficiency virus (HIV) emerged as a pandemic in the 1980s.
  • Significant advancements in diagnosis and management have transformed HIV from a terminal diagnosis to a manageable chronic condition.
  • Antiretroviral therapy (ART) is crucial for managing HIV infection.

Purpose of the Study:

  • To review the clinical considerations for managing HIV in pregnant individuals.
  • To discuss the ethical considerations in managing HIV during pregnancy and delivery.
  • To highlight the impact of modern antiretroviral therapy on HIV management.

Main Methods:

  • Literature review of clinical and ethical aspects of HIV management in pregnancy.
  • Analysis of the role of antiretroviral therapy in viral suppression and transmission prevention.
  • Synthesis of current guidelines and best practices for pregnant individuals with HIV.

Main Results:

  • Antiretroviral therapy durably suppresses HIV replication.
  • Effective ART preserves maternal health during pregnancy.
  • ART prevents mother-to-child HIV transmission.

Conclusions:

  • HIV infection is now a manageable chronic condition during pregnancy.
  • Comprehensive management strategies are essential for pregnant individuals with HIV.
  • Continued research and adherence to treatment guidelines are vital for optimal outcomes.