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Sustained Decline in Acute Gastroenteritis-Associated Hospitalizations and Outpatient Visits Among American

Scott P Grytdal1, Dana L Haberling2, Jordan L Kennedy2

  • 1Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia.

Journal of the Pediatric Infectious Diseases Society
|January 9, 2018
PubMed

Insights

The rotavirus vaccine uptake was examined in American Indian and Alaska Native children. Post-vaccine, acute gastroenteritis hospitalizations and visits remained below pre-vaccine levels, indicating sustained impact.

Area of Science:

  • Pediatric infectious diseases
  • Vaccinology
  • Public health surveillance

Background:

  • Rotavirus is a leading cause of acute gastroenteritis (AGE) in young children globally.
  • Vaccination is a key strategy to reduce rotavirus burden.
  • Understanding vaccine impact in specific populations is crucial for public health.

Purpose of the Study:

  • To assess rotavirus vaccine uptake among American Indian and Alaska Native (AI/AN) children.
  • To compare trends in AGE-associated hospitalizations and outpatient visits before and after rotavirus vaccine introduction in AI/AN children aged under 5 years.

Main Methods:

  • Retrospective analysis of hospitalization and outpatient visit data.
  • Comparison of AGE-associated visit rates in the pre- and post-vaccine periods.
  • Focus on AI/AN children under 5 years of age.

Main Results:

  • Data on rotavirus vaccine uptake was analyzed.
  • Trends in AGE-associated hospitalizations and outpatient visits were compared.
  • AGE-associated hospitalization and outpatient visit rates remained below prevaccine levels in AI/AN children.

Conclusions:

  • The rotavirus vaccination program shows sustained impact in reducing AGE-related healthcare utilization among AI/AN children.
  • Continued monitoring is essential to ensure long-term effectiveness of the rotavirus vaccine in this population.
  • Public health interventions effectively reduced rotavirus disease burden in a vulnerable pediatric group.

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