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Updated: Feb 16, 2026

Oral Administration of Rotenone using a Gavage and Image Analysis of Alpha-synuclein Inclusions in the Enteric Nervous System
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Oral Fluoroquinolone Administration and Interacting Substances: The Pediatric Diet Dilemma
Jeffrey L Butler1, Amanda L Hurst1
1Pharmacy Department, Children's Hospital Colorado, Aurora.
Abstract:
Concomitant administration of enteral fluoroquinolones (FQs) with divalent or trivalent cation-containing compounds results in a reduction in FQ bioavailability. A review of enteral FQ administration with regards to the timing of divalent or trivalent cation-containing compounds in pediatric patients revealed a high number of inappropriately administered FQs. Suggestions for reducing the number of inappropriately timed FQ administrations are presented here.
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