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Updated: Feb 16, 2026

Chemiluminescence-based Assays for Detection of Nitric Oxide and its Derivatives from Autoxidation and Nitrosated Compounds
Published on: February 16, 2022
Flow analysis with chemiluminescence detection: Recent advances and applications
Irina I Timofeeva1, Christina S Vakh1, Andrey V Bulatov1
1Department of Analytical Chemistry, Institute of Chemistry, Saint-Petersburg University, St.Petersburg State University, SPbSU, SPbU, 7/9 Universitetskayanab., St. Petersburg 199034, Russia.
Abstract:
This article highlights the most important developments in flow analysis with chemiluminescence (CL) detection, describing different flow systems that are compatible with CL detection, detector designs, commonly applied CL reactions and approaches to sample treatment. Recent applications of flow analysis with CL detection (focusing on outputs published since 2010) are also presented. Applications are classified by sample matrix, covering foods and beverages, environmental matrices, pharmaceuticals and biological fluids. Comprehensive tables are provided for each area, listing the specific sample matrix, CL reaction used, linear range, limit of detection and sample treatment for each analyte. Finally, recent and emerging trends in the field are also discussed.
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