Primary cutaneous aspergillosis caused by Aspergillus.fumigatus in an immunocompetent patient: A case report
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Published on: March 22, 2012
Xiaoyan Liu1, Jun Yang, Weiyuan Ma
1Department of Pulmonary Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China Department of Pulmonary Medicine, Ankang Central Hospital, Ankang Department of Dermatology, Qilu Hospital, Shandong University, Jinan, China.
Rationale:
Primary cutaneous aspergillosis in immunocompromised patients has been well described in extensive investigations. However, in immunocompetent hosts, primary cutaneous infection of aspergillus occurs rarely, and remains poorly characterized.
Patient Concerns:
We present a case of primary cutaneous aspergillosis manifested by erythematous plague covered with flava eschar.
Diagnoses:
The patient was diagnosed with primary cutaneous aspergillosis.
Interventions:
Treatments with oral itraconazole at a dose of 75 mg/d and local wound care with ciclopirox olamine ointment were administered.
Outcomes:
After half a month, a partial resolution and a decrease in tenderness indicated gradual improvement, and a complete remission was achieved 2 months later.
Lessons:
Primary cutaneous aspergillosis could occur in immunocompetent hosts. The initial lesions may appear in different forms, including macules, papules, nodules, or plaques. Repeated biopsy of a skin lesion for both culture and histopathology is needed.
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