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Focal segmental glomerulosclerosis in children complicated by posterior reversible encephalopathy syndrome

Magdalena Stârcea1, Cristina Gavrilovici1, Mihaela Munteanu1

  • 1Department of Pediatrics, St. Maria Children's Hospital, University of Medicine and Pharmacy "Grigore T. Popa" Iasi, România.

The Journal of International Medical Research
|January 10, 2018
PubMed

Insights

Posterior reversible encephalopathy syndrome (PRES) is an uncommon side effect of cyclosporine A (CsA). This case highlights PRES in a child with focal segmental glomerulosclerosis treated with CsA.

Area of Science:

  • Pediatric Nephrology
  • Neurology
  • Immunology

Background:

  • Posterior reversible encephalopathy syndrome (PRES) is an uncommon adverse effect associated with cyclosporine A (CsA) treatment.
  • PRES typically arises from impaired cerebral blood flow autoregulation in response to elevated blood pressure.
  • While often linked to immunosuppression in oncological and hematological conditions, PRES can occur in other pediatric settings.

Keywords:
Focal segmental glomerulosclerosischildrencyclosporine Aend-stage renal diseasehypertensionimmunosuppressive therapyposterior reversible encephalopathy syndromeseizure

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