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Related Concept Videos

Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

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Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
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Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
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Compared with pure water, the solubility of an ionic compound is less in aqueous solutions containing a common ion (one also produced by dissolution of the ionic compound). This is an example of a phenomenon known as the common ion effect, which is a consequence of the law of mass action that may be explained using Le Chȃtelier’s principle. Consider the dissolution of silver iodide:
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Signal Attenuation as a Rat Model of Obsessive Compulsive Disorder
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Chronic obsessive-compulsive disorder: prognostic factors.

Lucas J B van Oudheusden1, Merijn Eikelenboom1, Harold J G M van Megen2

  • 1Department of Psychiatry and EMGOInstitute,VU-University Medical Center, Academic Outpatient Clinic for Anxiety Disorders, GGZinGeest,Amsterdam,The Netherlands.

Psychological Medicine
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Summary

External factors like trauma and negative life events increase the risk of chronic obsessive-compulsive disorder (OCD). Illness-related factors, such as duration and severity, maintain chronicity, suggesting prevention is key.

Keywords:
Obsessive-compulsive disorderchronicitycourse of illness

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Epidemiology

Background:

  • Obsessive-compulsive disorder (OCD) exhibits significant variability in its illness course.
  • Predictors of a chronic OCD trajectory remain largely unknown.
  • Understanding chronicity factors is crucial for effective OCD management.

Purpose of the Study:

  • To identify factors that induce chronicity in OCD.
  • To identify factors that maintain chronicity in OCD.

Main Methods:

  • Utilized data from the Netherlands Obsessive Compulsive Disorder Association (NOCDA) study.
  • Included 270 subjects with a current OCD diagnosis.
  • Employed logistic regression to analyze 2-year follow-up chronicity status based on baseline predictors.

Main Results:

  • Psychotrauma, recent negative life events, and having a partner influenced the risk of becoming chronic.
  • Longer illness duration and higher illness severity increased the risk of remaining chronic.
  • Odds ratios indicated significant associations for these factors.

Conclusions:

  • External influences (stress, trauma) contribute to the onset of chronic OCD.
  • Illness-related factors (duration, severity) are key in maintaining chronicity.
  • Preventative strategies targeting stress and social support are recommended to avert chronicity.