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Updated: Feb 16, 2026

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Published on: August 25, 2015
Genomic Analyses and Precision Oncology in Gastroesophageal Cancer: Forwards or Backwards?
Raghav Sundar1, Patrick Tan2,3,4,5
1Department of Haematology-Oncology, National University Health System, Singapore.
Abstract:
Gastroesophageal adenocarcinoma (GEA) comprises a myriad of distinct subtypes with significant interpatient, intrapatient, and intratumor heterogeneity. Strategies for tackling molecular heterogeneity will be essential for the success of GEA precision oncology-in this regard, blood-based "liquid biopsies" may provide broader views of the real-time genomic landscape of this disease, identifying actionable biomarkers and monitoring therapy resistance. Cancer Discov; 8(1); 14-6. ©2018 AACRSee related article by Pectasides et al., p. 37See related article by Janjigian et al., p. 49.
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