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Updated: Feb 15, 2026

Dissecting the Non-human Primate Brain in Stereotaxic Space
Published on: July 16, 2009
Human entorhinal cortex represents visual space using a boundary-anchored grid
Joshua B Julian1, Alexandra T Keinath2, Giulia Frazzetta2
1Department of Psychology, University of Pennsylvania, Philadelphia, PA, USA. joshua.b.julian@gmail.com.
Abstract:
When participants performed a visual search task, functional MRI responses in entorhinal cortex exhibited a sixfold periodic modulation by gaze-movement direction. The orientation of this modulation was determined by the shape and orientation of the bounded search space. These results indicate that human entorhinal cortex represents visual space using a boundary-anchored grid, analogous to that used by rodents to represent navigable space.
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